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Ambrisentan is used in the treatment of pulmonary hypertension.
Ambrisentan relaxes the blood vessels of the lungs, which in turn lowers the blood pressure.
Peripheral edema, Sinus inflammation, Flushing (sense of warmth in the face, ears, neck and trunk), Nasal congestion
Tadalafil is used in the treatment of erectile dysfunction and pulmonary hypertension.It is also used in erectile dysfunction with benign prostatic hyperplasia (enlarged prostate).
Tadalafil is a phosphodiesterase (PDE-5) inhibitor. It works in erectile dysfunction by increasing blood flow to the penis by relaxing the muscles in penile blood vessels. It works in pulmonary hypertension by relaxing the blood vessels in the lungs to allow blood to flow more easily.
Headache, Nausea, Nasopharyngitis, Flushing (sense of warmth in the face, ears, neck and trunk), Dyspepsia, Muscle pain, Back pain, Pain in extremity